Allergy may be major cause in the development of asthma



Asthma is rampant in global society and affects people of all ages. It is a persistent inflammatory ailment of the bronchial tubes that results in swelling and contraction of the nose passage. Reports of World health organization revealed that millions of people are under grip from asthma and huge number of fatalities occur. Bourgeoning studies designate that asthma is developed through allergic reaction in which the airways of the lungs become oversensitive to some indoor and environmental pollutants. Biologists have established fast rate of asthma and the decisive role of allergens in the development of asthma.


It is established that the gene-environment interactions may be a major cause of asthma. In present scenario, it is heated theme of discussion and need to generate awareness about allergy induced asthma to grip the syndrome in social structure. Many medical scholars assert that allergy induced asthma is prevalent in world population when an individual is hypersensitive to certain allergen. It is predominant in young children who are more sensitive to aeroallergens that lead to persistent asthma symptoms at later stage of their life than children who have good immune system or resistance power.

Role of allergy in the development of asthma: 

Since ancient time, people has recognized the asthma as a common dilemma which affects the health care system and it is a prime source of undesirable healthcare outcomes. Asthma is characterized as a chronic respiratory disease which is caused by reversible airway hindrance and related with bronchial hyper sensitivity and airway swelling. Inflammation is developed through numerous indoor and environmental factors, known as an allergen. When these allergens attack to person, the air passages of the bronchus and lungs engorge and full of mucus. As a result, muscles within the bronchial tubules contract and create narrowing of the airways. In this condition, patient unable breathe from the lungs smoothly, have recurring periods of wheezing, chest tautness, and coughing. Allergy has major role in developing ailment of asthma. Exposure to the allergens may result into the pain or swelling in the respiratory system and leads to breathlessness. Presently, environment is highly polluted, therefore there are increased cases of allergy induced asthma.

Causes:

Plentiful researches have demonstrated that paediatric asthma is developed due to exposure of young children to common allergens such as contaminated foods, pets and environment. Allergic reaction greatly affects the lungs and airways and causes asthma symptoms. The main aeroallergens are sensitized are house dust mite (HDM), furred pets basically cat and dog, cockroach, mold, and rodent allergens. The allergen, contained in their droppings and transmitted in dust can prompt reaction at concentrations of only a few μg of allergen per gram of dust, far below normal concentrations found in homes. House dust mites and other allergens was the main carrier of allergic reaction that can lead to symptoms of asthma. Usually, mites may get healthy environment to grow in mattresses, box springs and pillows therefore these can attack easily on patent’s body.

Another major allergen that causes asthma is through animals. Cat allergen is considered to be the most dangerous of the pet allergens that is normally found in dust samples where a cat resides. Medical scholars investigated this factor and demonstrated that cat allergen exposure is coupled with the development of sensitivity and asthma. Mouse allergen has also vital role in the developing asthma. Other allergens like molds that can easily be scattered in dust, wood, paper, food and plants can cause asthma. They multiply at faster rate in humid environment. Allergy disease due to molds is caused by Alternaria, Aspergillus, Cladosporium and Penicillium spp. The major risk factor of moulds is the IgE-mediated sensitization.

Medical reports have confirmed the exposure to tobacco smoke via active smoking may cause lung disease. Especially children are more prone to environmental tobacco smoke in both prenatal and postnatal period when mother excessively smoke. This allergen deteriorates lung function and child show the symptoms of respiratory irritation, for example, cough, excess phlegm and breathe with difficulty. Genetic makeup of humans has major role in vulnerability to asthma. Clinical manifestation of Asthma is mainly dependent on complex interplay between genetic predisposition and environmental factors.



Treatment and prevention:

Asthma is preventable disease if appropriate diagnostic methods are used. It depends on the age of a person. Young children do not respond in positive way in the diagnosis process therefore physicians study the patient and family medical history to investigate the causes of asthma. Adults are diagnosed through a series of breathing capacity tests to find out the extent of asthma. In normal course, doctors do not use allergy test to determine the condition of asthma. Medical studies have represented that eliminating persistent allergens are effectual method to assuage allergy and asthma, but these cannot avert clinical symptoms of asthma.

There are number of medicines prescribed by the physician to treat allergy induced asthma which include steroids and inhalers. Tablets are often given to control allergic reactions which lessen the chances of developing asthma. It is highly suggested that treatment must be done under the supervision of certified doctor. Therapeutic technique such as immunotherapy is used in treating allergy induced asthma which involves injections of allergen extract into allergic patients. Immunotherapy is a systematic procedure of immune modulation to control the symptomatic condition of hypersensitivity reaction developed through IgE antibodies. But immunotherapy has some adverse impacts on the patient such as gastro intestinal disorder which limits its application.


The treatment of asthma is long-term process and some patient have to take medication whole life. It can be debated that numerous allergens like tobacco smoke and pets, food may trigger respiratory illnesses. But scientists do not have sufficient evidence to confirm that allergens and contaminants can decrease respiratory illnesses. The best possible way is to lessen the damaging effects from allergens, especially for sensitized individuals.

To bind up important details, it is well identified among world populace that asthma disease is a national health concern which spreads due to numerous allergens. Lung disease is predominant at great pace in developed countries which had major roots in allergic reaction. It has damaging impacts on the health of the affected individual, as well as society. There is a direct link between allergies and asthma but opponents debated that other condition also leads to asthma and people have wrong conception that allergens are the causes of developing asthma.

It has been observed that people who are sensitive to some allergen may display the symptoms of asthma. Main cause is the gene-environment interactions that lead to medical condition of asthma. Doctors recommend that in order to halt the symptoms of asthma, induced by allergy is to decrease the presence of allergens. Since the research on allergy induced asthma is still in initial stages and is debatable topic, there is a need to conduct further research on the role of allergy exposures in the home and other environment and the development of asthma. These may help to avert the disease in people.

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